Domenico Antonio Vaccaro (June 3, 1678 – June 13, 1745) was an Italian painter, sculptor and architect, the son and pupil of Lorenzo Vaccaro. Lorenzo was in turn a pupil of Cosimo Fanzago and was part of a large family of artists including Andrea Vaccaro, a pupil of Girolamo Imparato.
Domenico Antonio was born in Naples and his body of work is all in or near that city. Works of interest include a statue of Moses in the church of San Ferdinando, and the statues of Penitence and Solitude on the premises of the monastery (now museum) of San Martino.